Facing unexplained patchy hair loss in your dog can be unsettling. Alopecia X, a dermatological condition marked by patchy baldness, is a relatively common condition in particular breeds. While its exact cause remains unknown, understanding its symptoms, diagnosis, and potential treatment options hopefully allows you to manage this condition effectively. This guide explores Alopecia X, aiming to bring clarity and support to concerned dog owners.

What is Alopecia X in dogs?

Alopecia X in dogs is a pattern of baldness characterized by significant, patchy hair loss without the inflammation typically seen in other skin conditions.

The hair loss that occurs with Alopecia X mainly happens on the torso, where the dog's head and legs usually aren't affected. While it sounds serious, this condition doesn't make dogs sick in other ways; it's more of a cosmetic issue. It's seen more in certain breeds with thick fur, like Pomeranians, Chow Chows, and Nordic breeds.

Changes in the hair coat usually become noticeable during early adulthood, occurring between the ages of 1 and 10 years.

What are the causes of Alopecia X in dogs?

The exact causes of Alopecia X are not fully understood, but it is thought to relate to an imbalance in the dog's hair growth cycle.

Factors could include hormonal imbalances or genetic predispositions in certain breeds. It's not linked to any systemic signs of illness, making it primarily a cosmetic concern.

Researchers are exploring the role of growth hormones and adrenal gland function in affecting the hair follicle, aiming to better understand and manage this condition.

What are the symptoms of Alopecia X?

The symptoms of Alopecia X include noticeable hair loss in dogs, leading to thinning or completely bare patches, primarily on the trunks or torso. Your dog's head and legs are usually not affected.

One of the initial indicators is the shedding of guard hairs, which gives the fur a "puppy-coat" look. Additionally, the hair coat appears dull and feels dry to the touch.

The hair loss is symmetrical and often leaves the skin hyperpigmented (darker than usual). Unlike other conditions, Alopecia X doesn't cause itching or discomfort.

Alopecia X in a Pomeranian
Notice the patchy hair loss

How is Alopecia X diagnosed?

Diagnosing involves a thorough veterinary examination while considering your dog's history, breed, and clinical signs.

Unlike other endocrine disorders, Alopecia X occurs without underlying causes such as Cushing's disease, hypothyroidism, or sex hormone imbalances, making the diagnosis of Alopecia X a process of elimination.

When I'm examining a dog that has non-inflammatory alopecia that is symmetrical, I start by ruling out the endocrine disorders mentioned above. This includes a specialized test called ACTH stimulation to rule out Cushing's disease, and other blood work to rule out hypothyroidism.

Your veterinarian may also recommend a skin biopsy to help diagnose this condition by revealing hair cycle arrest and the presence of inactive hair follicles. With inactive hair follicles, the hair is more likely to fall out.

What is the treatment for Alopecia X in dogs?

There are various treatment options that we can explore for affected dogs. However, it's important to keep in mind that there is no guaranteed treatment for this condition.

Some options include:

  • Melatonin supplements: This hormone helps regulate hair growth and can promote the re-growth of hair in some dogs. It is effective in approximately 40% of dogs treated with melatonin.
  • Neutering: In male dogs, neutering can help decrease testosterone levels, which may contribute to the condition.
  • Growth hormones: In some cases, growth hormone therapy with deslorelin may help promote hair regrowth.
  • Trilostane: Trilostane is primarily used to treat Cushing's disease but can also be used to treat Alopecia X. Even though trilostane is thought to help dogs grow back hair by affecting certain hormones in their bodies, it's interesting that hair still grows even when there are higher levels of a hormone called 17-hydroxyprogesterone. This treatment requires constant monitoring for potential side effects.

Further management may involve taking protective measures when your dog is outside, such as using dog t-shirts or sweaters to shield the exposed skin from the elements.

It's important to note that every dog is different and what works for one may not work for another. Your veterinarian will work with you to find the best treatment plan for your dog based on their individual needs.

What is the prognosis for hair regrowth?

The prognosis for hair regrowth remains uncertain but does not affect their overall health. Hair regrowth following neutering surgery and medical treatment is variable and not guaranteed and there is a possibility of recurrences.

FAQs

Is alopecia X contagious?

No, it is not contagious. It's a dermatological condition tied to the dog's internal hormonal balance and hair growth cycle.

Can alopecia X be cured?

Currently, there's no known cure. However, treatments can help manage the condition and stimulate hair regrowth in some cases.

Can alopecia X cause other health problems?

This is primarily a cosmetic condition and doesn't directly cause other health issues. However, hair loss can expose the skin to potential risks like sunburn.


In summary, Alopecia X represents a somewhat frustrating yet primarily cosmetic challenge for dog owners, characterized by significant, patchy hair loss without underlying inflammation or systemic illness. Predominantly affecting plush-coated breeds in their early adulthood, its exact causes remain elusive, attributed to possible hormonal imbalances or genetic predispositions. Diagnosis is a process of elimination, distinguishing it from other endocrine disorders, with treatment options including melatonin supplements, neutering, growth hormone therapy, and trilostane, despite no guaranteed cure. Management focuses on symptom relief and protecting the exposed skin, with the prognosis for hair regrowth being uncertain but not detrimental to the dog's overall health.

If you suspect your dog has this condition or if your dog is currently being treated for it and you have questions, please reach out to your veterinarian. If you have a dog in Kitchener-Waterloo and would like personalized, expert care, please visit us here at Kingsdale Animal Hospital.